Name of Trainee
(Years in Program) |
Mentor(s) |
Publication (Authors, Year, Title, Journal, PMCID) |
McKay, Sonya L.
(1995-2001, PhD) |
Gellman |
1: McKay SL, Haptonstall B, Gellman SH.
Beyond the hydrophobic effect: attractions involving heteroaromatic rings in aqueous solution. |
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|
J Am Chem Soc. 2001 Feb 14;123(6):1244-5. |
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|
PMID: 11456685 [PubMed] |
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|
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2: Gardner RR, McKay SL, Gellman SH. |
|
|
Solvent-dependent stabilization of the E configuration of propargylic secondary |
|
|
amides. |
|
|
Org Lett. 2000 Jul 27;2(15):2335-8. |
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|
PMID: 10930277 [PubMed - indexed for MEDLINE] |
|
|
|
Woycechowsky, Kenneth J.
(1995-2002, PhD) |
Raines |
1: Woycechowsky KJ, Hook BA, Raines RT.
Catalysis of protein folding by an immobilized small-molecule dithiol. |
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|
Biotechnol Prog. 2003 Jul-Aug;19(4):1307-14. |
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|
PMID: 12892495 [PubMed - indexed for MEDLINE] |
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2: Woycechowsky KJ, Raines RT. |
|
|
The CXC motif: a functional mimic of protein disulfide isomerase. |
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|
Biochemistry. 2003 May 13;42(18):5387-94. |
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|
PMID: 12731880 [PubMed - indexed for MEDLINE] |
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3: Sweeney RY, Kelemen BR, Woycechowsky KJ, Raines RT. |
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|
A highly active immobilized ribonuclease. |
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|
Anal Biochem. 2000 Nov 15;286(2):312-4. No abstract available. |
|
|
PMID: 11067760 [PubMed - indexed for MEDLINE] |
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4: Woycechowsky KJ, Raines RT. |
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|
Native disulfide bond formation in proteins. |
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|
Curr Opin Chem Biol. 2000 Oct;4(5):533-9. Review. |
|
|
PMID: 11006541 [PubMed - indexed for MEDLINE] |
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5: Klink TA, Woycechowsky KJ, Taylor KM, Raines RT. |
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|
Contribution of disulfide bonds to the conformational stability and catalytic |
|
|
activity of ribonuclease A. |
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|
Eur J Biochem. 2000 Jan;267(2):566-72. |
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|
PMID: 10632727 [PubMed - indexed for MEDLINE] |
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6: Woycechowsky KJ, Wittrup KD, Raines RT. |
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|
A small-molecule catalyst of protein folding in vitro and in vivo. |
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|
Chem Biol. 1999 Dec;6(12):871-9. |
|
|
PMID: 10631515 [PubMed - indexed for MEDLINE] |
|
|
|
Schuster, Michael C.
(1995-2000 for PhD; 1994-2002 for MD/PhD) |
Kiessling |
1: Schuster MC, Mann DA, Buchholz TJ, Johnson KM, Thomas WD, Kiessling LL.
Parallel synthesis of glycomimetic libraries: targeting a C-type lectin. |
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|
Org Lett. 2003 May 1;5(9):1407-10. |
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|
PMID: 12713285 [PubMed - indexed for MEDLINE] |
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2: Burke SD, Zhao Q, Schuster MC, Kiessling LL. |
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|
Synergistic formation of soluble lectin clusters by a templated multivalent saccharide ligand. |
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|
J Am Chem Soc. 2000 May 10;122(18):4518-4519 |
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3: Schuster MC, Mortell KH, Hegeman AD, Kiessling LL |
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|
Neoglycopolymers produced by aqueous ring-opening metathesis polymerization: Decreasing saccharide density increases activity. |
|
|
J Mol Catal A: Chem. 1997 Feb 24;116(1-2):209-216. |
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|
Carr, Heather S.
(1995-2000, PhD) |
Burstyn |
1: Carr HS, Tran D, Reynolds MF, Burstyn JN, Spiro TG.
Activation of soluble guanylyl cyclase by four-coordinate metalloporphyrins: evidence for a role for porphyrin conformation. |
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|
Biochemistry. 2002 Aug 6;41(31):10149-57. |
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|
PMID: 12146980 [PubMed - indexed for MEDLINE] |
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2: Serfass L, Carr HS, Aschenbrenner LM, Burstyn JN. |
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|
Calcium ion downregulates soluble guanylyl cyclase activity: evidence for a |
|
|
two-metal ion catalytic mechanism. |
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|
Arch Biochem Biophys. 2001 Mar 1;387(1):47-56. |
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|
PMID: 11368183 [PubMed - indexed for MEDLINE] |
|
|
|
Elder, Amy M.
(1995-2000, PhD) |
Rich |
Elder AM, Rich DH.
Two syntheses of the 16- and 17-membered DEF ring systems of chloropeptin and complestatin. |
|
|
Org Lett. 1999 Nov 4;1(9):1443-6. |
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|
PMID: 10825992 [PubMed - indexed for MEDLINE] |
|
|
|
Strong, Laura E.
(1995-2000, PhD) |
Kiessling |
1: Kiessling LL, Gestwicki JE, Strong LE.
Synthetic multivalent ligands as probes of signal transduction. |
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|
Angew Chem Int Ed Engl. 2006 Apr 3;45(15):2348-68. Review. |
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|
PMID: 16557636 [PubMed - indexed for MEDLINE] |
|
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|
|
|
2: Gestwicki JE, Cairo CW, Strong LE, Oetjen KA, Kiessling LL. |
|
|
Influencing receptor-ligand binding mechanisms with multivalent ligand |
|
|
architecture. |
|
|
J Am Chem Soc. 2002 Dec 18;124(50):14922-33. |
|
|
PMID: 12475334 [PubMed - indexed for MEDLINE] |
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|
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3: Lamanna AC, Gestwicki JE, Strong LE, Borchardt SL, Owen RM, Kiessling LL. |
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|
Conserved amplification of chemotactic responses through chemoreceptor |
|
|
interactions. |
|
|
J Bacteriol. 2002 Sep;184(18):4981-7. |
|
|
PMID: 12193613 [PubMed - indexed for MEDLINE] |
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4: Gestwicki JE, Strong LE, Cairo CW, Boehm FJ, Kiessling LL. |
|
|
Cell aggregation by scaffolded receptor clusters. |
|
|
Chem Biol. 2002 Feb;9(2):163-9. |
|
|
PMID: 11880031 [PubMed - indexed for MEDLINE] |
|
|
|
|
|
5: Gestwicki JE, Strong LE, Borchardt SL, Cairo CW, Schnoes AM, Kiessling LL. |
|
|
Designed potent multivalent chemoattractants for Escherichia coli. |
|
|
Bioorg Med Chem. 2001 Sep;9(9):2387-93. |
|
|
PMID: 11553480 [PubMed - indexed for MEDLINE] |
|
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|
|
|
6: Gestwicki JE, Strong LE, Kiessling LL. |
|
|
Visualization of Single Multivalent Receptor-Ligand Complexes by Transmission |
|
|
Electron Microscopy |
|
|
Angew Chem Int Ed Engl. 2000 Dec 15;39(24):4567-4570. No abstract available. |
|
|
PMID: 11169672 [PubMed - as supplied by publisher] |
|
|
|
|
|
7: Kiessling LL, Gestwicki JE, Strong LE. |
|
|
Synthetic multivalent ligands in the exploration of cell-surface interactions. |
|
|
Curr Opin Chem Biol. 2000 Dec;4(6):696-703. Review. |
|
|
PMID: 11102876 [PubMed - indexed for MEDLINE] |
|
|
|
|
|
8: Gestwicki JE, Strong LE, Kiessling LL. |
|
|
Tuning chemotactic responses with synthetic multivalent ligands. |
|
|
Chem Biol. 2000 Aug;7(8):583-91. |
|
|
PMID: 11048949 [PubMed - indexed for MEDLINE] |
|
|
|
|
|
9: Gordon EJ, Gestwicki JE, Strong LE, Kiessling LL. |
|
|
Synthesis of end-labeled multivalent ligands for exploring |
|
|
cell-surface-receptor-ligand interactions. |
|
|
Chem Biol. 2000 Jan;7(1):9-16. |
|
|
PMID: 10662681 [PubMed - indexed for MEDLINE] |
|
|
|
|
|
10: Gordon EJ, Strong LE, Kiessling LL. |
|
|
Glycoprotein-inspired materials promote the proteolytic release of cell surface |
|
|
L-selectin. |
|
|
Bioorg Med Chem. 1998 Aug;6(8):1293-9. |
|
|
PMID: 9784870 [PubMed - indexed for MEDLINE] |
|
|
|
|
|
11: Kiessling LL, Strong LE, Gestwicki, JE. |
|
|
Principles for multivalent ligand design. |
|
|
Annu Rep in Med Chem. 2000;35:321-330. |
|
|
|
|
|
12: Strong LE, Kiessling LL. |
|
|
A general synthetic route to defined, biologically active multivalent arrays. |
|
|
J Am Chem Soc. 1999 Jul 7;121(26):6193-6196. |
|
|
|
|
|
13: Manning DD, Strong LE, Hu X, Beck PJ, Kiessling LL |
|
|
Neoglycopolymer inhibitors of the selectins. |
|
|
Tetrahedron 1997 Sep 1;53(35);11937-11952 |
|
|
|
Thiriot, David S.
(1995-2001, PhD) |
Ruoho |
1: Thiriot DS, Ruoho AE.
Mutagenesis and derivatization of human vesicle monoamine transporter 2 (VMAT2) cysteines identifies transporter domains involved in tetrabenazine binding and substrate transport. |
|
|
J Biol Chem. 2001 Jul 20;276(29):27304-15. Epub 2001 May 24. |
|
|
PMID: 11375404 [PubMed - indexed for MEDLINE] |
|
|
|
|
|
2: Thiriot DS, Sievert MK, Ruoho AE. |
|
|
Identification of human vesicle monoamine transporter (VMAT2) lumenal cysteines |
|
|
that form an intramolecular disulfide bond. |
|
|
Biochemistry. 2002 May 21;41(20):6346-53. |
|
|
PMID: 12009896 [PubMed - indexed for MEDLINE] |
|
|
|
|
|
3: Wu Z, Thiriot DS, Ruoho AE. |
|
|
Tyr199 in transmembrane domain 5 of the beta2-adrenergic receptor interacts |
|
|
directly with the pharmacophore of a unique fluorenone-based antagonist. |
|
|
Biochem J. 2001 Mar 15;354(Pt 3):485-91. |
|
|
PMID: 11237852 [PubMed - indexed for MEDLINE] |
|
|
|
|
|
4: Rong Y, Arbabian M, Thiriot DS, Seibold A, Clark RB, Ruoho AE. |
|
|
Probing the salmeterol binding site on the beta 2-adrenergic receptor using a |
|
|
novel photoaffinity ligand, [(125)I]iodoazidosalmeterol. |
|
|
Biochemistry. 1999 Aug 31;38(35):11278-86. |
|
|
PMID: 10471277 [PubMed - indexed for MEDLINE] |
|
|
|
|
|
5: Sievert MK, Thiriot DS, Edwards RH, Ruoho AE. |
|
|
High-efficiency expression and characterization of the synaptic-vesicle monoamine |
|
|
transporter from baculovirus-infected insect cells. |
|
|
Biochem J. 1998 Mar 1;330 ( Pt 2):959-66. |
|
|
PMID: 9480916 [PubMed - indexed for MEDLINE] |
|
|
|
Tseng, Ta-Sheng A.
(1995-2002, PhD) |
Burstyn |
Deck KM, Tseng TA, Burstyn JN.
Triisopropyltriazacyclononane copper(II): an efficient phosphodiester hydrolysis catalyst and DNA cleavage agent. |
|
|
Inorg Chem. 2002 Feb 25;41(4):669-77. |
|
|
PMID: 11849065 [PubMed - indexed for MEDLINE] |
|
|
|
Harper, Laura A.
(1996-2001, PhD) |
Vedejs |
Vedejs E, Daugulis O, Harper LA, MacKay JA, Powell DR.
A comparison of monocyclic and bicyclic phospholanes as acyl-transfer catalysts. |
|
|
J Org Chem. 2003 Jun 27;68(13):5020-7. |
|
|
PMID: 12816454 [PubMed] |
|
|
|
Werner, Elizabeth A.
(1996-2001, PhD) |
DeLuca |
1: Werner EA, Deluca HF.
Retinoic acid is detected at relatively high levels in the CNS of adult rats. |
|
|
Am J Physiol Endocrinol Metab. 2002 Mar;282(3):E672-8. |
|
|
PMID: 11832372 [PubMed - indexed for MEDLINE] |
|
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|
|
|
2: Werner EA, DeLuca HF. |
|
|
Metabolism of a physiological amount of all-trans-retinol in the vitamin |
|
|
A-deficient rat. |
|
|
Arch Biochem Biophys. 2001 Sep 15;393(2):262-70. |
|
|
PMID: 11556813 [PubMed - indexed for MEDLINE] |
|
|
|
Kremer, John J
(1997-2001, PhD) |
R. Murphy |
1: Kremer JJ, Murphy RM.
Kinetics of adsorption of beta-amyloid peptide Abeta(1-40) to lipid bilayers. |
|
|
J Biochem Biophys Methods. 2003 Aug 29;57(2):159-69. |
|
|
PMID: 12915007 [PubMed - indexed for MEDLINE] |
|
|
|
|
|
2: Kremer JJ, Sklansky DJ, Murphy RM. |
|
|
Profile of changes in lipid bilayer structure caused by beta-amyloid peptide. |
|
|
Biochemistry. 2001 Jul 24;40(29):8563-71. |
|
|
PMID: 11456496 [PubMed - indexed for MEDLINE] |
|
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|
|
|
3: Kremer JJ, Pallitto MM, Sklansky DJ, Murphy RM. |
|
|
Correlation of beta-amyloid aggregate size and hydrophobicity with decreased |
|
|
bilayer fluidity of model membranes. |
|
|
Biochemistry. 2000 Aug 22;39(33):10309-18. |
|
|
PMID: 10956020 [PubMed - indexed for MEDLINE] |
|
|
|
Kelly, Wendy L.
(1997-1998, MS) |
Lauhon |
None from Wisconsin; PhD with Townsend |
|
|
|
Singer, Steven W.
(1997-2001, PhD) |
Casey |
1: Casey CP, Johnson JB, Singer SW, Cui Q.
Hydrogen elimination from a hydroxycyclopentadienyl ruthenium(II) hydride: study of hydrogen activation in a ligand-metal bifunctional hydrogenation catalyst. |
|
|
J Am Chem Soc. 2005 Mar 9;127(9):3100-9. Erratum in: J Am Chem Soc. 2008 Jan |
|
|
23;130(3):1110. |
|
|
PMID: 15740149 [PubMed - indexed for MEDLINE] |
|
|
|
|
|
2: Casey CP, Singer SW, Powell DR, Hayashi RK, Kavana M. |
|
|
Hydrogen transfer to carbonyls and imines from a hydroxycyclopentadienyl |
|
|
ruthenium hydride: evidence for concerted hydride and proton transfer. |
|
|
J Am Chem Soc. 2001 Feb 14;123(6):1090-100. |
|
|
PMID: 11456662 [PubMed - indexed for MEDLINE] |
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|
|
|
3: Casey CP, Johnson JB, Singer SW, Cui Q |
|
|
Hydrogen elimination from a hydroxycyclopentadienyl ruthenium(II) hydride: Study of hydrogen activation in a ligand-metal bifunctional hydrogenation catalyst. |
|
|
J Am Chem Soc. 2005;127(9): 3100-3109. |
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|
|
|
4: Casey CP, Vos TE, Singer SW, Guzei IA |
|
|
Protonated aminocyclopentadienyl ruthenium hydride reduction of benzaldehyde and the conversion of the resulting ruthenium triflate to a ruthenium hydride with H-2 and base. |
|
|
Organometallics. 2002;21(23):5038-5046. |
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|
|
5: Casey CP, Singer SW, Powell DR. |
|
|
The role of a hydroxycyclopentadienyl ruthenium dicarbonyl formate in formic acid reductions of carbonyl compounds catalyzed by Shvo's diruthenium catalyst. |
|
|
Can J Chem. 2001;79(5):1002-1011 |
Gelman, Michael A
(1998-2003 PhD Training; 1996-2005 for MD/PhD) |
Gellmann |
1: Gelman MA, Weisblum B, Lynn DM, Gellman SH.
Biocidal activity of polystyrenes that are cationic by virtue of protonation. |
|
|
Org Lett. 2004 Feb 19;6(4):557-60. |
|
|
PMID: 14961622 [PubMed - indexed for MEDLINE] |
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|
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2: Gelman MA, Richter S, Cao H, Umezawa N, Gellman SH, Rana TM. |
|
|
Selective binding of TAR RNA by a Tat-derived beta-peptide. |
|
|
Org Lett. 2003 Oct 2;5(20):3563-5. |
|
|
PMID: 14507173 [PubMed - indexed for MEDLINE] |
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|
|
3: Umezawa N, Gelman MA, Haigis MC, Raines RT, Gellman SH. |
|
|
Translocation of a beta-peptide across cell membranes. |
|
|
J Am Chem Soc. 2002 Jan 23;124(3):368-9. |
|
|
PMID: 11792194 [PubMed - indexed for MEDLINE] |
|
|
|
Jenkins, Cara L.
(1998-2001, PhD) |
Raines |
1: Jenkins CL, Vasbinder MM, Miller SJ, Raines RT.
Peptide bond isosteres: ester or (E)-alkene in the backbone of the collagen triple helix. |
|
|
Org Lett. 2005 Jun 23;7(13):2619-22. |
|
|
PMID: 15957905 [PubMed - indexed for MEDLINE] |
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|
|
|
2: Jenkins CL, Thiyagarajan N, Sweeney RY, Guy MP, Kelemen BR, Acharya KR, Raines |
|
|
RT. |
|
|
Binding of non-natural 3'-nucleotides to ribonuclease A. |
|
|
FEBS J. 2005 Feb;272(3):744-55. |
|
|
PMID: 15670155 [PubMed - indexed for MEDLINE] |
|
|
|
|
|
3: Jenkins CL, Lin G, Duo J, Rapolu D, Guzei IA, Raines RT, Krow GR. |
|
|
Substituted 2-azabicyclo[2.1.1]hexanes as constrained proline analogues: |
|
|
implications for collagen stability. |
|
|
J Org Chem. 2004 Dec 10;69(25):8565-73. Erratum in: J Org Chem. 2006 Feb |
|
|
17;71(4):1754. |
|
|
PMID: 15575731 [PubMed - indexed for MEDLINE] |
|
|
|
|
|
4: Jenkins CL, McCloskey AI, Guzei IA, Eberhardt ES, Raines RT. |
|
|
O-acylation of hydroxyproline residues: effect on peptide-bond isomerization and |
|
|
collagen stability. |
|
|
Biopolymers. 2005;80(1):1-8. |
|
|
PMID: 15558658 [PubMed - indexed for MEDLINE] |
|
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|
|
5: Jenkins CL, Bretscher LE, Guzei IA, Raines RT. |
|
|
Effect of 3-hydroxyproline residues on collagen stability. |
|
|
J Am Chem Soc. 2003 May 28;125(21):6422-7. |
|
|
PMID: 12785781 [PubMed - indexed for MEDLINE] |
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|
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6: Jenkins CL, Raines RT. |
|
|
Insights on the conformational stability of collagen. |
|
|
Nat Prod Rep. 2002 Feb;19(1):49-59. Review. |
|
|
PMID: 11902439 [PubMed - indexed for MEDLINE] |
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|
|
7: Jardine AM, Leonidas DD, Jenkins CL, Park C, Raines RT, Acharya KR, Shapiro R. |
|
|
Cleavage of 3',5'-pyrophosphate-linked dinucleotides by ribonuclease A and |
|
|
angiogenin. |
|
|
Biochemistry. 2001 Aug 28;40(34):10262-72. |
|
|
PMID: 11513604 [PubMed - indexed for MEDLINE] |
|
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|
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8: Bretscher LE, Jenkins CL, Taylor KM, DeRider ML, Raines RT. |
|
|
Conformational stability of collagen relies on a stereoelectronic effect. |
|
|
J Am Chem Soc. 2001 Jan 31;123(4):777-8. No abstract available. |
|
|
PMID: 11456609 [PubMed - indexed for MEDLINE] |
|
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|
|
|
9: Mannino SJ, Jenkins CL, Raines RT. |
|
|
Chemical mechanism of DNA cleavage by the homing endonuclease I-PpoI. |
|
|
Biochemistry. 1999 Dec 7;38(49):16178-86. |
|
|
PMID: 10587440 [PubMed - indexed for MEDLINE] |
|
|
|
Lambert, William T.
(1998-2003, PhD) |
Burke |
1: Lambert WT, Hanson GH, Benayoud F, Burke SD.
Halichondrin B: synthesis of the C1-C22 subunit. |
|
|
J Org Chem. 2005 Nov 11;70(23):9382-98. |
|
|
PMID: 16268612 [PubMed - indexed for MEDLINE] |
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|
|
2: Guzei IA, Clark RW, Burke SD, Lambert WT. |
|
|
A comparison of the ring conformational properties of two derivatives prepared |
|
|
from the same diene diacetate precursor. |
|
|
Acta Crystallogr C. 2003 Dec;59(Pt 12):o721-3. Epub 2003 Nov 30. |
|
|
PMID: 14671382 [PubMed - indexed for MEDLINE] |
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|
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3: Lambert WT, Burke SD. |
|
|
Halichondrin B: synthesis of a C1-C14 model via desymmetrization of |
|
|
(+)-conduritol E. |
|
|
Org Lett. 2003 Feb 20;5(4):515-8. |
|
|
PMID: 12583757 [PubMed - indexed for MEDLINE] |
|
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|
|
|
4: Clark RW, Guzei IA, Ivanov SA, Burke SD, Lambert WT. |
|
|
The lack of C2 molecular symmetry in |
|
|
(1R,2R,3S,6S)-3,6-dibenzyloxycyclohex-4-ene-1,2-diol. |
|
|
Acta Crystallogr C. 2001 Jul;57(Pt 7):844-5. Epub 2001 Jul 9. |
|
|
PMID: 11443261 [PubMed - indexed for MEDLINE] |
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|
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5: Burke SD, Jung KW, Lambert WT, Phillips JR, Klovning JJ. |
|
|
Halichondrin B: synthesis of the C(1)-C(15) subunit. |
|
|
J Org Chem. 2000 Jun 30;65(13):4070-87. |
|
|
PMID: 10866625 [PubMed - indexed for MEDLINE] |
|
|
|
Buege, Laura L.
(1999-2000 MS) |
Mecozzi |
None. |
|
|
|
Ciolli, Christopher J.
(1999-2004, PhD) |
Belshaw |
1: Levitsky K, Boersma MD, Ciolli CJ, Belshaw PJ.
Exo-mechanism proximity-accelerated alkylations: investigations of linkers, electrophiles and surface mutations in engineered cyclophilin-cyclosporin systems. |
|
|
Chembiochem. 2005 May;6(5):890-9. |
|
|
PMID: 15832403 [PubMed - indexed for MEDLINE] |
|
|
|
|
|
2: Ciolli CJ, Kalagher S, Belshaw PJ. |
|
|
TRAM linker: a safety-catch linker for the traceless release of acrylamides. |
|
|
Org Lett. 2004 Jun 10;6(12):1891-4. |
|
|
PMID: 15176776 [PubMed - indexed for MEDLINE] |
|
|
|
|
|
3: Levitsky K, Ciolli CJ, Belshaw PJ. |
|
|
Selective inhibition of engineered receptors via proximity-accelerated |
|
|
alkylation. |
|
|
Org Lett. 2003 Mar 6;5(5):693-6. |
|
|
PMID: 12605492 [PubMed - indexed for MEDLINE] |
|
|
|
Fix, Shannon R.
(1999-2001, MS) |
Stahl |
1: Fix SR, Brice JL, Stahl SS.
Efficient intramolecular oxidative amination of olefins through direct dioxygen-coupled palladium catalysis. |
|
|
Angew Chem Int Ed Engl. 2002 Jan 4;41(1):164-6. No abstract available. |
|
|
PMID: 12491473 [PubMed - indexed for MEDLINE] |
|
|
|
|
|
2: Steinhoff BA, Fix SR, Stahl SS. |
|
|
Mechanistic study of alcohol oxidation by the Pd(OAc)(2)/O(2)/DMSO catalyst |
|
|
system and implications for the development of improved aerobic oxidation catalysts. |
|
|
J Am Chem Soc. 2002 Feb 6;124(5):766-7. |
|
|
PMID: 11817948 [PubMed - indexed for MEDLINE] |
|
|
|
Odegard, Amy L.
(1999-2004, PhD) |
Nibert |
1: Nibert ML, Odegard AL, Agosto MA, Chandran K, Schiff LA.
Putative autocleavage of reovirus mu1 protein in concert with outer-capsid disassembly and activation for membrane permeabilization. |
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J Mol Biol. 2005 Jan 21;345(3):461-74. |
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PMID: 15581891 [PubMed - indexed for MEDLINE] |
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2: Odegard AL, Chandran K, Zhang X, Parker JS, Baker TS, Nibert ML. |
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Putative autocleavage of outer capsid protein micro1, allowing release of |
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|
myristoylated peptide micro1N during particle uncoating, is critical for cell |
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|
entry by reovirus. |
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|
J Virol. 2004 Aug;78(16):8732-45. |
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PMID: 15280481 [PubMed - indexed for MEDLINE] |
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3: Odegard AL, Chandran K, Liemann S, Harrison SC, Nibert ML. |
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|
Disulfide bonding among micro 1 trimers in mammalian reovirus outer capsid: a |
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|
late and reversible step in virion morphogenesis. |
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|
J Virol. 2003 May;77(9):5389-400. |
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PMID: 12692241 [PubMed - indexed for MEDLINE] |
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|
Zakrzewski, Laura L.
(1999-2001, MS) |
Mecozzi |
None. |
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|
|
Sprague, Christopher L.
(1999-2004, PhD) |
Elfarra |
1: Sprague CL, Elfarra AA.
Protection of rats against 3-butene-1,2-diol-induced hepatotoxicity and hypoglycemia by N-acetyl-l-cysteine. |
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Toxicol Appl Pharmacol. 2005 Sep 15;207(3):266-74. |
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PMID: 16129119 [PubMed - indexed for MEDLINE] |
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2: Sprague CL, Elfarra AA. |
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|
Mercapturic acid urinary metabolites of 3-butene-1,2-diol as in vivo evidence for |
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|
the formation of hydroxymethylvinyl ketone in mice and rats. |
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Chem Res Toxicol. 2004 Jun;17(6):819-26. |
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PMID: 15206903 [PubMed - indexed for MEDLINE] |
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3: Sprague CL, Phillips LA, Young KM, Elfarra AA. |
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|
Species and tissue differences in the toxicity of 3-butene-1,2-diol in male |
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Sprague-Dawley rats and B6C3F1 mice. |
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Toxicol Sci. 2004 Jul;80(1):3-13. Epub 2004 May 5. |
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PMID: 15129020 [PubMed - indexed for MEDLINE] |
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4: Sprague CL, Elfarra AA. |
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|
Detection of carboxylic acids and inhibition of hippuric acid formation in rats |
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|
treated with 3-butene-1,2-diol, a major metabolite of 1,3-butadiene. |
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|
Drug Metab Dispos. 2003 Aug;31(8):986-92. Erratum in: Drug Metab Dispos. 2003 Sep |
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|
31(9):1198. |
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|
PMID: 12867486 [PubMed - indexed for MEDLINE] |
|
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|
Voight, Eric A.
(1999-2004, PhD) |
Burke |
1: Marvin CC, Voight EA, Burke SD.
Synthesis of (+)-didemniserinolipid B via ketalization/ring-closing metathesis. |
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|
Org Lett. 2007 Dec 20;9(26):5357-9. Epub 2007 Nov 30. |
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PMID: 18047361 [PubMed - indexed for MEDLINE] |
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2: Wysocki LM, Dodge MW, Voight EA, Burke SD. |
|
|
Stereochemically general approach to adjacent bis(tetrahydrofuran) cores of |
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|
annonaceous acetogenins. |
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|
Org Lett. 2006 Nov 23;8(24):5637-40. |
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PMID: 17107091 [PubMed - indexed for MEDLINE] |
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3: Voight EA, Seradj H, Roethle PA, Burke SD. |
|
|
Synthesis of the bryostatin 1 northern hemisphere (C1-C16) via desymmetrization |
|
|
by ketalization/ring-closing metathesis. |
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|
Org Lett. 2004 Oct 28;6(22):4045-8. |
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|
PMID: 15496095 [PubMed - indexed for MEDLINE] |
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4: Voight EA, Roethle PA, Burke SD. |
|
|
Concise formal synthesis of the bryostatin southern hemisphere (C17-C27). |
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|
J Org Chem. 2004 Jun 25;69(13):4534-7. |
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|
PMID: 15202915 [PubMed - indexed for MEDLINE] |
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5: Voight EA, Rein C, Burke SD. |
|
|
Synthesis of sialic acids via desymmetrization by ring-closing metathesis. |
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|
J Org Chem. 2002 Nov 29;67(24):8489-99. |
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|
PMID: 12444630 [PubMed - indexed for MEDLINE] |
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6: Burke SD, Voight EA. |
|
|
Formal synthesis of (+)-3-deoxy-D-glycero-D-galacto-2-nonulosonic acid (KDN) via |
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|
desymmetrization by ring-closing metathesis. |
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|
Org Lett. 2001 Jan 25;3(2):237-40. |
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|
PMID: 11430043 [PubMed - indexed for MEDLINE] |
|
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|
Erwin, Whitney M.
(2000-2006, PhD) |
Lauhon |
Lauhon CT, Erwin WM, Ton GN.
Substrate specificity for 4-thiouridine modification in Escherichia coli. |
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|
J Biol Chem. 2004 May 28;279(22):23022-9. Epub 2004 Mar 22. |
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|
PMID: 15037613 [PubMed - indexed for MEDLINE] |
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|
Hinderaker, Matthew P.
(2000-2001, MS) |
Raines |
1: Arnold U, Hinderaker MP, Köditz J, Golbik R, Ulbrich-Hofmann R, Raines RT.
Protein prosthesis: a nonnatural residue accelerates folding and increases stability. |
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|
J Am Chem Soc. 2003 Jun 25;125(25):7500-1. |
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|
PMID: 12812474 [PubMed - indexed for MEDLINE] |
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2: Arnold U, Hinderaker MP, Raines RT. |
|
|
Semisynthesis of ribonuclease A using intein-mediated protein ligation. |
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|
ScientificWorldJournal. 2002 Jun 28;2:1823-7. |
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|
PMID: 12806173 [PubMed - indexed for MEDLINE] |
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|
|
3: Hinderaker MP, Raines RT. |
|
|
An electronic effect on protein structure. |
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|
Protein Sci. 2003 Jun;12(6):1188-94. |
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|
PMID: 12761389 [PubMed - indexed for MEDLINE] |
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4: Arnold U, Hinderaker MP, Nilsson BL, Huck BR, Gellman SH, Raines RT. |
|
|
Protein prosthesis: a semisynthetic enzyme with a beta-peptide reverse turn. |
|
|
J Am Chem Soc. 2002 Jul 24;124(29):8522-3. |
|
|
PMID: 12121081 [PubMed - indexed for MEDLINE] |
|
|
|
Cherney, Mellisa M.
(2001-2007, PhD) |
Burstyn |
1: Cherney MM, Pazicni S, Frank N, Marvin KA, Kraus JP, Burstyn JN.
Ferrous human cystathionine beta-synthase loses activity during enzyme assay due to a ligand switch process. |
|
|
Biochemistry. 2007 Nov 13;46(45):13199-210. Epub 2007 Oct 23. |
|
|
PMID: 17956124 [PubMed - indexed for MEDLINE] |
|
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|
|
2: Pazicni S, Cherney MM, Lukat-Rodgers GS, Oliveriusová J, Rodgers KR, Kraus JP, |
|
|
Burstyn JN. |
|
|
The heme of cystathionine beta-synthase likely undergoes a thermally induced redox-mediated ligand switch. |
|
|
Biochemistry. 2005 Dec 27;44(51):16785-95. |
|
|
PMID: 16363792 [PubMed - indexed for MEDLINE] |
|
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|
|
3: Clark RW, Youn H, Parks RB, Cherney MM, Roberts GP, Burstyn JN. |
|
|
Investigation of the role of the N-terminal proline, the distal heme ligand in the CO sensor CooA. |
|
|
Biochemistry. 2004 Nov 9;43(44):14149-60. |
|
|
PMID: 15518565 [PubMed - indexed for MEDLINE] |
|
|
|
Clare, Brian H.
(2001-2002 MS) |
Gellman/Abbott |
1: Clare BH, Guzman O, de Pablo JJ, Abbott NL.
Measurement of the azimuthal anchoring energy of liquid crystals in contact with oligo(ethylene glycol)-terminated self-assembled monolayers supported on obliquely deposited gold films. |
|
|
Langmuir. 2006 May 9;22(10):4654-9. |
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|
PMID: 16649778 [PubMed - indexed for MEDLINE] |
|
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|
|
2: Clare BH, Abbott NL. |
|
|
Orientations of nematic liquid crystals on surfaces presenting controlled |
|
|
densities of peptides: amplification of protein-peptide binding events. |
|
|
Langmuir. 2005 Jul 5;21(14):6451-61. |
|
|
PMID: 15982053 [PubMed - indexed for MEDLINE] |
|
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|
|
|
3: Clare TL, Clare BH, Nichols BM, Abbott NL, Hamers RJ. |
|
|
Functional monolayers for improved resistance to protein adsorption: |
|
|
oligo(ethylene glycol)-modified silicon and diamond surfaces. |
|
|
Langmuir. 2005 Jul 5;21(14):6344-55. |
|
|
PMID: 15982041 [PubMed - indexed for MEDLINE] |
|
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|
|
4: Lasseter TL, Clare BH, Abbott NL, Hamers RJ. |
|
|
Covalently modified silicon and diamond surfaces: resistance to nonspecific |
|
|
protein adsorption and optimization for biosensing. |
|
|
J Am Chem Soc. 2004 Aug 25;126(33):10220-1. |
|
|
PMID: 15315415 [PubMed - indexed for MEDLINE] |
|
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|
|
|
5: Clare BH, Guzman O, de Pablo J, Abbott NL. |
|
|
Anchoring energies of liquid crystals measured on surfaces presenting |
|
|
oligopeptides. |
|
|
Langmuir. 2006 Aug 29;22(18):7776-82. |
|
|
PMID: 16922563 [PubMed - indexed for MEDLINE] |
|
|
|
Miller, Reagan
(2001-2006 PhD) |
Lee |
1: Kim M, Miller RL, Lee D.
Cross and ring-closing metathesis of 1,3-diynes: metallotropic [1,3]-shift of ruthenium carbenes. |
|
|
J Am Chem Soc. 2005 Sep 21;127(37):12818-9. |
|
|
PMID: 16159273 [PubMed - indexed for MEDLINE] |
|
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|
|
2: Maifeld SV, Miller RL, Lee D. |
|
|
Group-selective ring-closing enyne metathesis: concentration-dependent selectivity profile of alkynylsilyloxy-tethered dienynes. |
|
|
J Am Chem Soc. 2004 Oct 6;126(39):12228-9. |
|
|
PMID: 15453731 [PubMed - indexed for MEDLINE] |
|
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|
|
3: Miller RL, Maifeld SV, Lee D. |
|
|
Ruthenium-catalyzed silyl ether formation and enyne metathesis sequence: synthesis of siloxacycles from terminal alkenyl alcohols and alkynylsilanes. |
|
|
Org Lett. 2004 Aug 5;6(16):2773-6. |
|
|
PMID: 15281766 [PubMed - indexed for MEDLINE] |
|
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|
|
4: Maifeld SV, Miller RL, Lee D. |
|
|
Activation of silanes by Grubbs' carbene complex Cl-2(PCy3)(2)Ru=CHPh: dehydrogenative condensation of alcohols and hydrosilylation of carbonyls. |
|
|
Tetrahedron Lett. 2002;43(36):6363-6366. |
|
|
|
Scharon, Aracelis J.
(2001-2003 MS) |
|
1: Kwon HJ, Smith WC, Scharon AJ, Hwang SH, Kurth MJ, Shen B.
C-O bond formation by polyketide synthases. |
|
|
Science. 2002 Aug 23;297(5585):1327-30. |
|
|
PMID: 12193782 [PubMed - indexed for MEDLINE] |
|
|
|
Wolfe, Marcus
(2001-2002 MS) |
Ludden |
1: Wolfe MT, Heo J, Garavelli JS, Ludden PW.
Hydroxylamine reductase activity of the hybrid cluster protein from Escherichia coli. |
|
|
J Bacteriol. 2002 Nov;184(21):5898-902. |
|
|
PMID: 12374823 [PubMed - indexed for MEDLINE] |
|
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|
|
|
2: Heo J, Wolfe MT, Staples CR, Ludden PW. |
|
|
Converting the NiFeS carbon monoxide dehydrogenase to a hydrogenase and a |
|
|
hydroxylamine reductase. |
|
|
J Bacteriol. 2002 Nov;184(21):5894-7. |
|
|
PMID: 12374822 [PubMed - indexed for MEDLINE] |
|
|
|
English, Emily (Payne)
(2002-2007 PhD) |
Gellman |
1: Chi Y, English EP, Pomerantz WC, Horne WS, Joyce LA, Alexander LR, Fleming WS, Hopkins EA, Gellman SH.
Practical synthesis of enantiomerically pure beta2-amino acids via proline-catalyzed diastereoselective aminomethylation of aldehydes. |
|
|
J Am Chem Soc. 2007 May 9;129(18):6050-5. Epub 2007 Apr 17. |
|
|
PMID: 17439122 [PubMed - indexed for MEDLINE] |
|
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|
|
2: English EP, Chumanov RS, Gellman SH, Compton T. |
|
|
Rational development of beta-peptide inhibitors of human cytomegalovirus entry. |
|
|
J Biol Chem. 2006 Feb 3;281(5):2661-7. Epub 2005 Nov 7. |
|
|
PMID: 16275647 [PubMed - indexed for MEDLINE] |
|
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|
|
|
3: Peelen TJ, Chi Y, English EP, Gellman SH. |
|
|
Synthesis of 4,4-disubstituted 2-aminocyclopentanecarboxylic acid derivatives and |
|
|
their incorporation into 12-helical beta-peptides. |
|
|
Org Lett. 2004 Nov 25;6(24):4411-4. |
|
|
PMID: 15548038 [PubMed - indexed for MEDLINE] |
|
|
|
Kolonko, Erin E. (McElroy)
(2002-2008 PhD) |
Kiessling |
1: Kolonko EM, Kiessling LL.
A polymeric domain that promotes cellular internalization. |
|
|
J Am Chem Soc. 2008 Apr 30;130(17):5626-7. Epub 2008 Apr 8. No abstract. |
|
|
PMID: 18393495 [PubMed - in process] |
|
|
|
|
|
2: Borrok MJ, Kolonko EM, Kiessling LL. |
|
|
Chemical probes of bacterial signal transduction reveal that repellents stabilize |
|
|
and attractants destabilize the chemoreceptor array. |
|
|
ACS Chem Biol. 2008 Feb 15;3(2):101-9. |
|
|
PMID: 18278851 [PubMed - indexed for MEDLINE] |
|
|
|
Johnson, Heather D.
(2002-2007 PhD) |
Thorson |
None. |
|
|
|
Kutz, Kimberly K. (Naber)
(2002-2006 PhD) |
Li |
1: Fu Q, Kutz KK, Schmidt JJ, Hsu YW, Messinger DI, Cain SD, de la Iglesia HO, Christie AE, Li L.
Hormone complement of the Cancer productus sinus gland and pericardial organ: an anatomical and mass spectrometric investigation. |
|
|
J Comp Neurol. 2005 Dec 26;493(4):607-26. |
|
|
PMID: 16304631 [PubMed - indexed for MEDLINE] |
|
|
|
|
|
2: Yew JY, Kutz KK, Dikler S, Messinger L, Li L, Stretton AO. |
|
|
Mass spectrometric map of neuropeptide expression in Ascaris suum. |
|
|
J Comp Neurol. 2005 Aug 8;488(4):396-413. |
|
|
PMID: 15973679 [PubMed - indexed for MEDLINE] |
|
|
|
|
|
3: Kutz KK, Schmidt JJ, Li L. |
|
|
In situ tissue analysis of neuropeptides by MALDI FTMS in-cell accumulation. |
|
|
Anal Chem. 2004 Oct 1;76(19):5630-40. |
|
|
PMID: 15456280 [PubMed - indexed for MEDLINE] |
|
|
|
|
|
4: DeKeyser SS, Kutz-Naber KK, Schmidt JJ, Barrett-Wilt GA, Li L. |
|
|
Imaging mass spectrometry of neuropeptides in decapod crustacean neuronal tissues. |
|
|
J Proteome Res. 2007 May;6(5):1782-91. Epub 2007 Mar 24. |
|
|
PMID: 17381149 [PubMed - indexed for MEDLINE] |
|
|
|
|
|
5: Christie AE, Kutz-Naber KK, Stemmler EA, Klein A, Messinger DI, Goiney CC, |
|
|
Conterato AJ, Bruns EA, Hsu YW, Li L, Dickinson PS. |
|
|
Midgut epithelial endocrine cells are a rich source of the neuropeptides |
|
|
APSGFLGMRamide (Cancer borealis tachykinin-related peptide Ia) and |
|
|
GYRKPPFNGSIFamide (Gly1-SIFamide) in the crabs Cancer borealis, magister, and productus. |
|
|
J Exp Biol. 2007 Feb;210(Pt 4):699-714. |
|
|
PMID: 17267655 [PubMed - indexed for MEDLINE] |
|
|
|
|
|
6: Ma M, Kutz-Naber KK, Li L. |
|
|
Methyl esterification assisted MALDI FTMS characterization of the orcokinin |
|
|
neuropeptide family. |
|
|
Anal Chem. 2007 Jan 15;79(2):673-81. |
|
|
PMID: 17222036 [PubMed - indexed for MEDLINE] |
|
|
|
|
|
7: Saideman SR, Ma M, Kutz-Naber KK, Cook A, Torfs P, Schoofs L, Li L, Nusbaum |
|
|
MP. |
|
|
Modulation of rhythmic motor activity by pyrokinin peptides. |
|
|
J Neurophysiol. 2007 Jan;97(1):579-95. Epub 2006 Oct 25. |
|
|
PMID: 17065249 [PubMed - indexed for MEDLINE] |
|
|
|
|
|
8: Cruz-Bermúdez ND, Fu Q, Kutz-Naber KK, Christie AE, Li L, Marder E. |
|
|
Mass spectrometric characterization and physiological actions of GAHKNYLRFamide, a novel FMRFamide-like peptide from crabs of the genus Cancer. |
|
|
J Neurochem. 2006 May;97(3):784-99. Epub 2006 Mar 3. |
|
|
PMID: 16515542 [PubMed - indexed for MEDLINE] |
|
|
|
Marvin, Christopher C.
(2002-2007 PhD) |
Burke |
1: Marvin CC, Voight EA, Burke SD.
Synthesis of (+)-didemniserinolipid B via ketalization/ring-closing metathesis. |
|
|
Org Lett. 2007 Dec 20;9(26):5357-9. Epub 2007 Nov 30. |
|
|
PMID: 18047361 [PubMed - indexed for MEDLINE] |
|
|
|
|
|
2: Marvin CC, Clemens AJ, Burke SD. |
|
|
Synthesis of thromboxane B2 via ketalization/ring-closing metathesis. |
|
|
Org Lett. 2007 Dec 20;9(26):5353-6. Epub 2007 Nov 30. |
|
|
PMID: 18047355 [PubMed - indexed for MEDLINE] |
|
|
|
Restituyo, Jose
(2002-2006 PhD) |
Rajski |
1: Restituyo JA, Comstock LR, Petersen SG, Stringfellow T, Rajski SR.
Conversion of aryl azides to O-alkyl imidates via modified Staudinger ligation. |
|
|
Org Lett. 2003 Nov 13;5(23):4357-60. |
|
|
PMID: 14601999 [PubMed] |
|
|
|
|
|
2: Mays JR, Restituyo JA, Katzenberger RJ, Wassarman DA, Rajski SR. |
|
|
Cyclic disulfides as functional mimics of the histone deacetylase inhibitor FK-228. |
|
|
Tetrahedron Lett. 2007 Jun 25;48(26):4579-4583. |
|
|
|
Bennett, Stephanie L.
(2003 MS) |
Kiessling |
None. |
|
|
|
Mays, Jared R.
(2003-2007 PhD) |
Rajski |
1: Mays JR, Weller Roska RL, Sarfaraz S, Mukhtar H, Rajski SR.
Identification, synthesis, and enzymology of non-natural glucosinolate chemopreventive candidates. |
|
|
Chembiochem. 2008 Mar 25;9(5):729-47. |
|
|
PMID: 18327862 [PubMed - in process] |
|
|
|
|
|
2: Mays JR, Restituyo JA, Katzenberger RJ, Wassarman DA, Rajski SR. |
|
|
Cyclic disulfides as functional mimics of the histone deacetylase inhibitor FK-228. |
|
|
Tetrahedron Lett. 2007 Jun 25;48(26):4579-4583. |
|
|
|
Sanchez, Ramon O.
(2003-2004) |
Burke |
None. |
|
|
|
Wezeman, Rachel J.
(2005-2006 MS) |
Blackwell |
1: Geske GD, O'Neill JC, Miller DM, Wezeman RJ, Mattmann ME, Lin Q, Blackwell HE.
Comparative analyses of N-acylated homoserine lactones reveal unique structural features that dictate their ability to activate or inhibit quorum sensing. |
|
|
Chembiochem. 2008 Feb 15;9(3):389-400. |
|
|
PMID: 18224645 [PubMed - in process] |
|
|
|
|
|
2: Geske GD, Wezeman RJ, Siegel AP, Blackwell HE. |
|
|
Small molecule inhibitors of bacterial quorum sensing and biofilm formation. |
|
|
J Am Chem Soc. 2005 Sep 21;127(37):12762-3. |
|
|
PMID: 16159245 [PubMed - indexed for MEDLINE] |
Poppe, Claire
(2006-2007 MS) |
Furgeson |
None. |