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Handout
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1z2r
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2hyd
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Approaches to Biochemistry.pdf
Outline & homework assignment
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Biochemistry of catalytic RNAs (revised) PDF slides
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Biochemistry of catalytic RNAs (revised) powerpoint
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Biochemistry of catalytic RNAs - Goals and Assignments
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Characterizing Enzyme Kinetic Mechanisms and Substrate/Ligand Binding
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Chromatin PDF slides; 4/page
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Chromatin Powerpoint
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Course Outline and Assignment
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How to write a review.pdf
Resource for writing your critique
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Information on April 8 and April 15 lectures
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Learning how to be a scientist.pdf
Resource for writing your critique
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Lecture 1 PDF Sldes
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Study Guide
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Ten ways to write a better grant.pdf
Resource for writing your critique
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Homework
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Nucleosome and chromatin fiber dynamics
(Assigned: 3/20/2008 - Due: 3/25/2008)
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Learning How to Be a Scientist
(Assigned: 3/20/2008 - Due: 3/25/2008)
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Reading
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1981, DeLuca
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1983, Reeve
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1986, Bikle
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1_Glotzer etal 1991.pdf
Paper for critique Due 04-29-08
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2004, DeLuca
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2006, Germain
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2006, VanHooke
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2_Hunt etal 1992.pdf
Paper for critique Due 04-29-08
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3_Murray and Kirschner 1989.pdf
Paper for critique Due 04-29-08
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4_Murray etal 1989.pdf
Paper for critique Due 04-29-08
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Bell & Dutta Review
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Biol. Chem., 2007, Fedora et al
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Biol. Chem., 2007, Valadkhan
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Cell Division.pdf
Background reading
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Cell, 2000
Structural Biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily
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Chapter 43.pdf
Background reading
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Cyclin Classic Exp.pdf
Background reading
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JACS Articles, 2002
An ultrahigh resolution structure of TEM-1 B-lactamase suggests a role for glu166 as the general base in acylation
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JMB, 2003
Structure of MsbA from Vibrio cholera: A multidrug resistance ABC transporter homolog in a closed conformation
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Key regulators of the cell cycle hold promise.pdf
Background reading
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Kirschner 1999.pdf
Optional background reading
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Molecular Cell, 2003
A Tweezers-like motion of the ATP-binding cassette dimer in an ABC Transport Cycle
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Molecular Cell, 2006, Hamill and Pyle
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Murray 2004.pdf
Optional background reading
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Nature Articles, 2006
Structure of a bacterial multidrug ABC transporter
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Nguyen et al
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Randell et al
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Salvation of Doug.pdf
Background reading
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Science 293, 1793 (2001)
Structure of MsbA from E. coli: A homolog of the multidrug resistance ATP binding cassette (ABC) transporters
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Weinreich et al
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