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Cleland Lab -The Multifunctional Enzyme Pyruvate Carboxylase
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The enzymatic carboxylation reaction of pyruvate by Pyruvate Carboxylase is being investigated using kinetics, mutagenesis, 13C and 18O isotope effects and X-ray crystallography (in collaboration with the Rayment laboratory)
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Carb synthesis sheds light on promising tuberculosis drug target
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Tom Record Recepient of the 2009 Hugh M. Huffman Award
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