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Weibel Lab - Controlling the interface between bacterial cells and their environment
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Microstructured materials are beginning to have an impact on
microbiology. They make it possible to isolate, manipulate, and study
single cells of bacteria and can be combined with chemical biology,
biochemistry, genetics, optical microscopy, and scanning probe
microscopy to study microbial physiology.
We are using materials--such as the microelectrode array shown
above--to isolate and manipulate hundreds of individual cells of
bacteria in parallel and study the dynamics of structural proteins that
play a role in controlling cell shape. Tracking the dynamics of
proteins in a large number of cells using spatial and time-resolved
epifluorescence microscopy makes it possible for us to explore their
function quantitatively.
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Learn more about research by Douglas B. Weibel
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