News 2004
 
May 4, 2004
 
Elvehjem Award   

John W. Suttie, professor emeritus, biochemistry, has received the Conrad A. Elvehjem Award from the American Society for Nutritional Sciences in recognition of his outstanding service to nutrition as a scientist, editor, adviser and communicator on behalf of the profession.



May 3, 2004
 
Osborn Mendel Award   

James Ntambi, professor, nutritional sciences and biochemistry, has received the Osborne Mendel Award from the American Society for Nutritional Sciences for outstanding contributions toward the understanding of adipocyte differentiation and the regulation of gene expression involved in lipid metabolism.



May 2, 2004
 
Elizabeth Craig wins Hilldale Award   

Craig has been a member of the faculty since 1979, and also served as chair of the Department of Biomolecular Chemistry from 1996-2002.

Her work on protein folding and proteins involved in that process led to her election to the National Academy of Sciences in 1998 and to the American Academy of Arts and Sciences in 2000. She was also selected to the American Academy of Microbiology.

During her career, Craig has been a leader in efforts to understand a class of proteins known as molecular chaperones. These proteins aid in the important processes of folding and translocation of newly synthesized proteins in all organisms. A number of genetic diseases, including Huntington's, Alzheimer's and Creutzfeldt Jacob diseases are caused by defects in protein folding.
She held the WARF (Elizabeth Cavert Miller) professorship from 1992-97 and the H.I. Romnes Faculty Fellowship from 1985-90.

Craig earned a bachelor's degree in bacteriology at the University of Rhode Island and a doctorate in microbiology at the Washington University School of Medicine.



May 1, 2004
 
Wisconsin chemists find a new chink in TB's armor   

The family of bacteria that causes tuberculosis (TB) and leprosy are notoriously sturdy. And although the diseases they cause have been held in check for the past 50 years by antibiotics, some strains are becoming increasingly resistant to existing therapy.

Now, however, a new chink has been found in the cellular armor that makes these infectious diseases difficult to treat. The discovery, reported today (May 9) in the online editions of the journal Nature Structural & Molecular Biology by a team of chemists and biochemists from the University of Wisconsin-Madison, opens the door to the development of a new family of antibiotics to treat diseases that still claim as many as 3 million lives annually worldwide.

"Most of the treatments we have for these diseases date from the 1950s," says Laura L. Kiessling, a UW-Madison professor of chemistry and the leader of the team reporting the new discovery. "Many traditional antibiotics don't work against tuberculosis."

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April 6, 2004
 
Everson Lecture in Biochemistry   

April 6, 2004 3:30 pm

Room B1118 Biochemistry, 420 Henry Mall
Claire Walczak

Department of Biochemistry & Molecular Biology, Indiana University
Molecular Mechanisms of Mitosis: A Cellular Tug-of-War

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February 2, 2004
 
DHEA boosts growth rate of human neural stem cells   

Human neural stem cells, exposed in a lab dish to the steroid DHEA, exhibit a remarkable uptick in growth rates, suggesting that the hormone may play a role in helping the brain produce new cells, according to a new study published this week in the online editions of the Proceedings of the National Academy of Sciences (PNAS).

The new work, conducted by a team of scientists at the University of Wisconsin-Madison, provides some of the first direct evidence of the biological effects of DHEA on the human nervous system, according to Clive Svendsen, the study's senior author and an authority on brain stem cells at UW-Madison's Waisman Center.

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February 1, 2004
 
Department Poster Session and Awards    

The Annual Biochemistry Awards Reception included two new awards this year, made possible by the generosity of Arnold E. and Catherine M. Denton.

Graduate Teaching Excellence Award: Michael D. Hobbs
This award is intended to recognize a Biochemistry graduate student who has consistently shown evidence of quality, commitment, and innovation in teaching. Graduate students who have completed their Biochemistry major teaching requirements are eligible. Nominations are requested from all instructors of Biochemistry classes with graduate teaching assistants. Nominations for students who have assisted in more than one class during their two semesters of required teaching should be presented as joint nominations between all involved instructors. These nominations should indicated student responsibilities, class and/or discussion/lab size, and characteristics that distinguish the nominee from other graduate assistants. In addition to the items listed above, student evaluations will be used as part of the selection criteria for qualified candidates.

Graduate Mentoring Award: Kimberly Dickson
This award is designated to honor Biochemistry graduate students who consistently provide quality guidance and scientific training in mentoring undergraduate students in their research efforts. Qualified nominees should be nearing completion of their degree and have established a consistent record of mentoring undergraduates throughout their career. The nomination will consist of a cover letter from the laboratory PI highlighting the candidate?s contributions tot eh intellectual and technical training of undergraduate lab members, including evidence of a successful scientific learning experience such as abstracts, poster presentations, or co-authored publications. Letters of support from undergraduate students should also be included with the nomination. These letters of support are of particular importance to this nomination and should provide strong testimonial to the candidate?s mentoring achievements.

Sigrid Leirmo Memorial Award in Biochemistry: David S. Bernstein
This award is provided by funds given in memory of Dr. Sigrid Leirmo by her husband. Dr. Leirmo received her Ph.D. degree in the Department of Biochemistry (1989) and was a postdoctoral research associate in the Department of Bacteriology when she died tragically in an accident in October, 1990. This award is designated for a graduate or postdoctoral student who best exemplifies her spirit. Sigrid was widely acknowledged among her fellow students and colleagues both as a promising researcher and as an enthusiastic friend and mentor. The award is to be given to a postdoctoral or graduate student who is acknowledged by his/her peers and advisors as one who displays clear promise as a research scientist. Most importantly, the award is to be designated in appreciation of the student?s consistent willingness to contribute to the intellectual and technical potential of his or her fellow students and colleagues through the selfless help of others.



January 2, 2004
 
Brendan Orner is the recipient of the 2004 Paul D. Boyer Postdoctoral Excellence Award   

Brendan will speak on the topic of The Design and Fabrication of Arrays for the Combinatorial Exploration of Cell Adherence on Monday January 26th at 3:30 in room B1118 Biochemistry.

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January 1, 2004
 
Winter weather turns on flowering gene   

In four months, when flower buds spring up from the ground, you may wonder how plants know it's time to bloom. This question has baffled plant biologists for years. Now, scientists at the University of Wisconsin-Madison have an answer: a gene that functions as an alarm clock to rouse certain plants from a vegetative state in the winter to a flowering state in the spring.

According to the researchers, the findings, published in the Jan. 8 issue of the journal Nature, could lead to new methods for manipulating the productivity of crop plants, as well as a better understanding of how organisms control the fate of their cells.

Most people may not know that some of our favorite salad ingredients - carrots, cabbage, radishes, beets and parsley - take two seasons to flower and produce seeds because we harvest them before they have the chance to flower. These plants, called biennials, require a season of cold to flower.

"We've known that winter does something to the plant's growing tip, or meristem, and makes it competent to flower," says Richard Amasino, a UW-Madison biochemistry professor and senior author of the paper. "If biennials don't go through winter, they won't flower." But why, he adds, has remained a mystery.

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