Thursday, July 30th, 2009
|
| 4:00 - 5:45 pm |
Reception and Registration
Pick up conference materials at Khorana Auditorium (Room 175 Biochemistry Addition, 433 Babcock Drive) |
| Time |
Speaker |
Talk Title
|
Session 1: General
|
| 6:00 pm |
Aseem Ansari
UW-Madison
|
Welcome
|
| 6:05 - 6:20 |
Uttam RajBhandary
MIT
|
Comments |
| 6:20 - 6:40 |
Marvin Caruthers
University of CO-Boulder
|
Nucleic Acid Chemistry: From Gobind to the Present |
6:40 - 7:00
|
Peter Kim
Merck
|
Viral Membrane Fusion and its Inhibition |
| 7:00 - 7:20 |
Henry Lardy
UW-Madison
|
The Metabolism and Function of Dehydroepiandrosterone |
| 7:20 - 7:40 |
Marshall Nirenberg
National Institute of Health
|
Deciphering the Genetic Code |
| 7:40 - 8:00 |
Marsha Rosner
University of Chicago
|
Regulation of Tumor Metastasis by MAP Kinase and MicroRNAs |
Friday, July 31st, 2009
|
| Time |
Speaker
|
Talk Title
|
Session 2: Nucleic Acids
|
8:30 am
|
Continental Breakfast
|
9:00 - 9:05
|
Chair: Hara Ghosh
|
Comments |
| 9:05 - 9:25 |
Robert Wells
Texas A&M |
Non-B DNA Conformations, Mutagenesis and Disease |
| 9:25 - 9:45 |
Hikoya Hayatsu
Okayama University |
Bisulfite Modification of Nucleotides: Mechanistic Consideration leading to improved Protocols of DNA Methylation Analysis |
| 9:45 - 10:05 |
Sankar Adhya
National Cancer Institute |
The Puzzle of Prophage λ Stability |
| 10:05 - 10:25 |
Dieter Söll
Yale |
The Genetic Code Revisited – Four Decades after Francis Crick |
| 10:25 - 10:45 |
Coffee Break |
| 10:45 - 10:50 |
Chair: Takao Sekiya
|
Comments |
| 10:50 - 11:10 |
Li Niu
University at Albany
|
One RNA Aptamer Sequence, Two Structures: A Collaborating Pair that Competitively Inhibits AMPA Receptors |
| 11:10 - 11:30 |
Hans-Joachim Fritz
Georg-August-Universitat |
The Hopeful Cornucopia - A study into Combinatorial Gene Synthesis |
| 11:30 - 11:50 |
Eiko Ohtsuka
AIST |
Efficient Synthesis of Oligonucleotide Conjugates on Solid-Support Using an (Aminoethoxycarbonyl) aminohexyl Group for 5’-Terminal Modification
|
| 11:50 - 12:10 |
Simon Chang
LSU |
The First Crystallographic Structure of Mammalian Phosphofructokinase from Rabbit Skeletal Muscle |
12:10 - 1:45
|
Lunch and the Poster Session
|
Session 3: Membranes, Receptors and Signaling
|
| 1:45 - 1:50 |
Chair: Pere Garriga
|
Comments |
| 1:50 - 2:10 |
Julius Adler
UW-Madison |
Gobind Khorana and My Current Research on Drosophila Behavior |
| 2:10 - 2:30 |
Marie-Alda Gilles-Gonzalez
UT Southwestern |
Oxygen Control of Cyclic di-GMP Homeostasis |
| 2:30 - 2:50 |
Wayne Hubbell
UCLA |
Gobind Khorana and the “Central Dogma” of Receptor Activation |
| 2:50 - 3:10 |
Thomas Sakmar
Rockefeller |
Heptahelical Receptors: Ligand Recognition and Conformational Dynamics in Bilayers |
| 3:10 - 3:30 |
David Farrens
Oregon Health & Science |
Dynamics of G-Protein Coupled Receptor (GPCR) Activation and Attenuation: Insights from Fluorescence Studies |
| 3:30 - 4:00 |
Break |
| 4:00 - 4:05 |
Chair: Umesh Varshney |
Comments |
| 4:05 - 4:25 |
John Hwa
Dartmouth |
Pharmacogenetics of the Human Prostacyclin Receptor: “hIP, SNiP COX and Vioxx” |
| 4:25 - 4:45 |
Kevin Ridge
University of Texas |
Signaling via Structure Change: NMR Analysis of GPCR and G protein Activation |
| 4:45 - 5:05 |
Judith Klein-Seetharaman
University of Pittsburgh |
Learning from Rhodopsin about Metabotropic Glutamate Receptors |
| 5:05 - 5:25 |
Peter Besmer
Sloan-Kettering |
Oncogenic Kit Receptor Signaling and Targeted Molecular Therapies – in Mouse Models of Gastrointestinal Stromal Tumor |
Saturday, August 1st, 2009
|
| Time |
Speaker |
Talk Title |
Session 4: Genes and Regulation
|
8:00 am
|
Continental Breakfast
|
| 8:25 - 8:30 |
Co-Chairs: Molly Jahn & Masayasu Nomura |
Comments |
| 8:30 - 8:55 am |
Mark Ptashne
Sloan Kettering |
Binding Reactions: Epigenetic Switches, Signal Transduction, Evolution and Cancer |
| 8:55 - 9:20 |
Peter Dervan
Caltech |
Transcription Factors as Targets for Cancer Therapy |
| 9:20 - 9:45 |
Phillip Sharp
MIT |
RNA as a Gene Regulation Modality |
| 9:45 - 10:05 |
James Dahlberg
UW-Madison |
Dissecting the roles of X. laevis miRNAs and Ago proteins in RISC activity |
| 10:05 - 10:30 |
Ronald Breaker
Yale
|
Large Structured Non-coding RNAs Revealed by Bacterial Metagenome Analysis |
| 10:30 - 10:45 |
Coffee Break |
Session 5: Genomes, Networks, Systems and Molecular Medicine
|
| 10:45 - 10:50 |
Chair: Lloyd Smith |
Comments |
| 10:50 - 11:15 |
Lee Hood
Systems Biology |
Systems Biology, Transforming Technologies and the Emergence of P4 Medicine (Predictive, Personalized, Preventive and Participatory) |
| 11:15 - 11:40 |
Richard Young
Whitehead Institute MIT |
Programming Cell State |
| 11:40 - 12:05 |
Patrick Brown
Stanford |
The "Dark Matter" of Biological Regulation?
|
| 12:05 - 12:25 |
Audrey Gasch
UW-Madison |
Acquired Stress Resistance in Yeast: Multiple Means to the Same End
|
12:30 - 2:30
|
Lunch and the Poster Session (Continued)
|
Session 6: Rewiring Cell Fate and Signaling Pathways
|
| 2:30 - 2:35 |
Chair: Jennifer Reed |
Comments |
| 2:35 - 2:55 |
James Thomson
UW-Madison |
Human Induced Pluripotent Stem Cells Derived with Episomal Vectors |
| 2:55 - 3:20 |
Wendell Lim
UCSF |
Biological Innovation: The Evolution and Engineering of New Signaling Systems
|
| 3:20 - 3:40 |
Laura Kiessling
UW-Madison |
Chemical Probes of Receptor Assembly in Signaling |
Session 7: Rewiring Genes and Networks (Biofuels)
|
| 3:40 - 3:45 |
Chair: Tim Donohue |
Comments |
| 3:45 - 4:10 |
Jay Keasling
Berkeley |
Synthetic Biology for Synthetic Fuels |
| 4:10 - 4:30 |
Robert Landick
UW-Madison |
Genome-scale Chromosomal Engineering of Bacterial Hosts for Bioenergy Production |
| 4:30 - 4:45 |
Break |
Session 8A: Origins and Designing Life - Synthetic Life
|
| 4:45 - 4:50 |
Chair: Aseem Ansari |
|
| 4:50 - 5:15 |
Hamilton Smith
J. Craig Venter Institute |
Making a Synthetic Cell |
| 5:15 - 5:40 |
George Church
Harvard Medical |
Reading and Writing Genomes |
| 5:40 - 6:05 |
George Whitesides
Harvard |
Questions about Questions about the Origin of Life |
| 6:05 - 6:30 |
Alta Charo
UW-Madison |
Synthetic Biology in Ethical Perspective |
| 7:00 - 9:00 |
Banquet (Pyle Center - Alumni Lounge, 702 Langdon Street)
Violin Concerto - Ptashne with Adrian Levine & Sara Sitzer
Banquet speaker - William Dove |
Sunday, August 2nd, 2009
|
| Time |
Speaker |
Talk Title |
Session 8B: Origins and Designing Life - Synthetic Genes and Genomes
|
8:00 am
|
Continental Breakfast
|
| 8:25 - 8:30 |
Chair: Nicole Perna |
Comments |
| 8:30 - 8:50 am |
Fredrick Blattner
UW-Madison |
Reducing the genome of E. coli: a top down approach to synthetic biology
|
| 8:50 - 9:15 |
Thomas Knight
MIT |
|
| 9:15 - 9:40 |
Rob Phillips
Caltech |
The Physics of Genome Management |
Session 9: Nano-Devices and Biomachines
|
| 9:40 - 9:45 |
Co-Chairs: Franco Cerrina & George Phillips |
Comments |
| 9:45 - 10:10 |
Nadrian Seeman
New York University |
DNA: Not Merely the Secret of Life |
| 10:10 - 10:35 |
William Shih
Harvard Medical |
Programmable Self-assembly of DNA into Nanoscale Three-dimensional Shapes |
| 10:35 - 10:55 |
Ryan Kershner
UW-Madison |
Top Down Meets Bottom Up: Controlled Placement of DNA Nanostructures |
Session 10: Development, Disease and Drug Design
|
| 10:55 - 11:00 |
Co-Chairs: James Ntambi & Hasan Mukhtar |
Comments |
| 11:00 - 11:25 |
Michael Levine
Berkeley |
Transcriptional Precision in the Drosophila Embryo |
| 11:25 - 11:45 |
Alan Attie
UW-Madison |
Gene Networks and Type 2 Diabetes |
| 11:45 - 12:05 |
James Bradner
Dana-Farber Cancer Institute |
Direct Inhibition of the Notch Transactivation Complex |
|
|
|
| 12:05 - 12:25 |
Waclaw Szybalski
UW-Madison |
Closing Remarks |
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